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 * Do you want to know more Side effects of TBHQ? look this slide.. **

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A. SIDE EFFECT **Generally side effect of TBHQ (tertiary butylhidroquinone)** is In high doses, it has some negative health effects on lab animals, such as precursors to stomach tumors and damage to DNA Consuming high doses of TBHQ (between 1 and 4 grams, approximately) can lead to a variety of :

1. Negative Symptoms ** Negative symptoms ** are thoughts, feelings, or behaviors normally present that are absent or diminished in a person with a mental disorder. Examples of negative symptoms are social withdrawal, apathy (decreased motivation), poverty of speech (brief replies), inability to experience pleasure (anhedonia), limited emotional expression, or defects in attention control. The term "negative symptoms" is specifically used for describing schizophrenia, but sometimes used more generally in reference to disorders such as depression or ** dementia **. These symptoms may be associated with alte red brainwave activity or brain damage. They can be more difficult to diagnose than Positive Symptoms, delusions, bizarre behavior, or formal thought disorder) because they represent a lesser degree of normal, desirable activity rather than the presence of undesirable or bizarre behavior. (Sandra L. Friedrich, M.A.)

2. Nausea and Vomiting (Ringing in the ears)

**Tinnitus** is the perception of sound within the human ear in the absence of corresponding external sound. Tinnitus is not a disease, but a Symptom that can result from a wide range of underlying causes: abnormally loud sounds in the ear canal for even the briefest period (but usually with some duration), ear infection, foreign objects in the ear, nose allergies that prevent (or induce) fluid drain, or wax build-up. Withdrawal from a benzodiazepine addiction may cause Tinnitus as well. In-ear headphones via sound entered directly into the ear canal itself, without any opportunity to be deflected or absorbed elsewhere are a popular cause of Tinnitus with volume set beyond modest or moderate levels.(www.wikipedia.com) 3. Delirium **Delirium** (acute confusional state) is a common and severe neuropsychiatric syndrome with core features of acute onset and fluctuating course, attentional deficits and generalized severe disorganization of behavior. It typically involves other cognitive deficits, changes in arousal (hyperactive, hypoactive, or mixed), perceptual deficits, altered sleep-wake cycle, and psychotic features such as hallucinations and delusions. It is often caused by a disease process 'outside' the brain, such as common forms of infection (UTI, pneumonia) or by drug effects, particularly anticholinergic or other CNS depressants (benzodiazapenes and opioids).

B. DOSAGE As a food additive, the FDA allows TBHQ to make up no more than 0.02 percent of the total oils in a food. Consuming up to a gram of TBHQ can cause variable toxicity, and up to 5 grams can be fatal. For perspective, it would take 312.5 McDonald's chicken nuggets (if they contain a full 0.02% of TBHQ) to consume a single gram.

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